A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells

Relative up-regulation of the Ikaros family transcription factor Helios in natural regulatory T cells (Tregs) has been reported by several groups. However, a role for Helios in regulatory T cells has not yet been described. Here, we show that Helios is upregulated in CD4(+)CD25(+) regulatory T cells...

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Main Authors: Getnet, Derese, Grosso, Joseph F., Goldberg, Monica V., Harris, Timothy J., Yen, Hung-Rong, Bruno, Tullia C., Durham, Nicholas M., Hipkiss, Edward L., Pyle, Kristin J., Wada, Satoshi, Pan, Fan, Pardoll, Drew M., Drake, Charles G.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060613/
https://ncbi.nlm.nih.gov/pubmed/20226531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.02.001
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