Caricamento...

Probing Mechanisms of Photoreceptor Degeneration in a New Mouse Model of the Common Form of Autosomal Dominant Retinitis Pigmentosa due to P23H Opsin Mutations

Rhodopsin, the visual pigment mediating vision under dim light, is composed of the apoprotein opsin and the chromophore ligand 11-cis-retinal. A P23H mutation in the opsin gene is one of the most prevalent causes of the human blinding disease, autosomal dominant retinitis pigmentosa. Although P23H c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sakami, Sanae, Maeda, Tadao, Bereta, Grzegorz, Okano, Kiichiro, Golczak, Marcin, Sumaroka, Alexander, Roman, Alejandro J., Cideciyan, Artur V., Jacobson, Samuel G., Palczewski, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060508/
https://ncbi.nlm.nih.gov/pubmed/21224384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209759
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !