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Gcn1 and Actin Binding to Yih1: IMPLICATIONS FOR ACTIVATION OF THE eIF2 KINASE GCN2
Yeast Yih1 protein and its mammalian ortholog IMPACT, abundant in neurons, are inhibitors of Gcn2, a kinase involved in amino acid homeostasis, stress response, and memory formation. Like Gcn2, Yih1/IMPACT harbors an N-terminal RWD domain that mediates binding to the Gcn2 activator Gcn1. Yih1 compet...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060488/ https://ncbi.nlm.nih.gov/pubmed/21239490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171587 |
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