Lataa...

Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells

GCN2 stimulates GCN4 translation in amino acid-starved cells by phosphorylating the α-subunit of translation initiation factor 2. GCN2 function in vivo requires the GCN1/GCN20 complex, which binds to the N-terminal domain of GCN2. A C-terminal segment of GCN1 (residues 2052–2428) was found to be nec...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sattlegger, Evelyn, Hinnebusch, Alan G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC305848/
https://ncbi.nlm.nih.gov/pubmed/11101534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6622
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!