Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells

Gelijkaardige items

• Gcn1 and Actin Binding to Yih1: IMPLICATIONS FOR ACTIVATION OF THE eIF2 KINASE GCN2
  door: Sattlegger, Evelyn, et al.
  Gepubliceerd in: (2011)
• Dimerization by Translation Initiation Factor 2 Kinase GCN2 Is Mediated by Interactions in the C-Terminal Ribosome-Binding Region and the Protein Kinase Domain
  door: Qiu, Hongfang, et al.
  Gepubliceerd in: (1998)
• The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation
  door: Qiu, Hongfang, et al.
  Gepubliceerd in: (2001)
• Enhanced Interaction between Pseudokinase and Kinase Domains in Gcn2 stimulates eIF2α Phosphorylation in Starved Cells
  door: Lageix, Sebastien, et al.
  Gepubliceerd in: (2014)
• Association of GCN1–GCN20 regulatory complex with the N-terminus of eIF2α kinase GCN2 is required for GCN2 activation
  door: Garcia-Barrio, Minerva, et al.
  Gepubliceerd in: (2000)