Mutations that bypass tRNA binding activate the intrinsically defective kinase domain in GCN2

مواد مشابهة

• The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation
  بواسطة: Qiu, Hongfang, وآخرون
  منشور في: (2001)
• Dimerization by Translation Initiation Factor 2 Kinase GCN2 Is Mediated by Interactions in the C-Terminal Ribosome-Binding Region and the Protein Kinase Domain
  بواسطة: Qiu, Hongfang, وآخرون
  منشور في: (1998)
• Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo
  بواسطة: Lageix, Sebastien, وآخرون
  منشور في: (2015)
• Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells
  بواسطة: Sattlegger, Evelyn, وآخرون
  منشور في: (2000)
• Defects in tRNA Processing and Nuclear Export Induce GCN4 Translation Independently of Phosphorylation of the α Subunit of Eukaryotic Translation Initiation Factor 2
  بواسطة: Qiu, Hongfang, وآخرون
  منشور في: (2000)