Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury

Glucocorticoids (GCs) are known inhibitors of wound healing. In this study we report the novel finding that both keratinocytes in vitro and epidermis in vivo synthesize cortisol and how this synthesis regulates wound healing. We show that epidermis expresses enzymes essential for cortisol synthesis,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vukelic, Sasa, Stojadinovic, Olivera, Pastar, Irena, Rabach, Morgan, Krzyzanowska, Agata, Lebrun, Elizabeth, Davis, Stephen C., Resnik, Sydney, Brem, Harold, Tomic-Canic, Marjana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060481/
https://ncbi.nlm.nih.gov/pubmed/21239489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188268
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