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Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury
Glucocorticoids (GCs) are known inhibitors of wound healing. In this study we report the novel finding that both keratinocytes in vitro and epidermis in vivo synthesize cortisol and how this synthesis regulates wound healing. We show that epidermis expresses enzymes essential for cortisol synthesis,...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060481/ https://ncbi.nlm.nih.gov/pubmed/21239489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188268 |
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