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Deregulation of epidermal stem cell niche contributes to pathogenesis of non-healing venous ulcers
The epidermis is maintained by epidermal stem cells (ESC) that reside in distinct niches and contribute to homeostasis and wound closure. Keratinocytes at the non-healing edges of venous ulcers (VUs) are healing-incompetent, hyper-proliferative and non-migratory suggesting deregulation of ESCs. To d...
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| Publicado no: | Wound Repair Regen |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329920/ https://ncbi.nlm.nih.gov/pubmed/24635172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/wrr.12142 |
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