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Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth

Carcinoma associated fibroblasts (CAFs) that express α-smooth-muscle-actin (αSMA) contribute to cancer progression, but their precise origin and role is unclear. Using mouse models of inflammation-induced gastric cancer, we show that at least 20% of CAFs originate from bone marrow (BM) and derive fr...

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Bibliografski detalji
Glavni autori: Quante, Michael, Tu, Shui Ping, Tomita, Hiroyuki, Gonda, Tamas, Wang, Sophie S.W., Takashi, Shigeo, Baik, Gwang Ho, Shibata, Wataru, DiPrete, Bethany, Betz, Kelly S., Friedman, Richard, Varro, Andrea, Tycko, Benjamin, Wang, Timothy C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060401/
https://ncbi.nlm.nih.gov/pubmed/21316604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.01.020
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