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Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy?
It is increasingly recognized that the non-neoplastic stromal compartment in most solid cancers plays an active role in tumor proliferation, invasion and metastasis. Cancer associated fibroblasts (CAFs) are one of the most abundant cell types in the tumor stroma, and these cells are pro-tumorigenic....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531978/ https://ncbi.nlm.nih.gov/pubmed/19840860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.10.001 |
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