Mechanism of topology simplification by type II DNA topoisomerases
Type II DNA topoisomerases actively reduce the fractions of knotted and catenated circular DNA below thermodynamic equilibrium values. To explain this surprising finding, we designed a model in which topoisomerases introduce a sharp bend in DNA. Because the enzymes have a specific orientation relati...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061029098 |
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