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Dynamics of site juxtaposition in supercoiled DNA

Juxtaposition kinetics between specific sites in supercoiled DNA is investigated at close to physiological ionic conditions by Brownian dynamics simulations. At such conditions, supercoiled DNA is interwound, and the probability of spatial site juxtaposition is much higher than in relaxed DNA. We fi...

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Bibliographic Details
Main Authors: Huang, Jing, Schlick, Tamar, Vologodskii, Alexander
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC14693/
https://ncbi.nlm.nih.gov/pubmed/11158579
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