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Dynamics of site juxtaposition in supercoiled DNA

Juxtaposition kinetics between specific sites in supercoiled DNA is investigated at close to physiological ionic conditions by Brownian dynamics simulations. At such conditions, supercoiled DNA is interwound, and the probability of spatial site juxtaposition is much higher than in relaxed DNA. We fi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Huang, Jing, Schlick, Tamar, Vologodskii, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.968
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