Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell

The analysis of genomic distribution of retroviral vectors is a powerful tool to monitor ‘vector-on-host’ effects in gene therapy (GT) trials but also provides crucial information about ‘host-on-vector’ influences based on the target cell genetic and epigenetic state. We had the unique occasion to c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Biasco, Luca, Ambrosi, Alessandro, Pellin, Danilo, Bartholomae, Cynthia, Brigida, Immacolata, Roncarolo, Maria Grazia, Di Serio, Clelia, von Kalle, Christof, Schmidt, Manfred, Aiuti, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2011
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060339/
https://ncbi.nlm.nih.gov/pubmed/21243617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000108
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi