Fluoride-Mediated Capture of a Noncovalent Bound State of a Reversible Covalent Enzyme Inhibitor: X-ray Crystallographic Analysis of an Exceptionally Potent α-Ketoheterocycle Inhibitor of Fatty Acid Amide Hydrolase

Lignende værker

• X-ray Crystallographic Analysis of α-Ketoheterocycle Inhibitors Bound to a Humanized Variant of Fatty Acid Amide Hydrolase
  af: Mileni, Mauro, et al.
  Udgivet: (2010)
• Optimization of the Central Heterocycle of α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase
  af: Garfunkle, Joie, et al.
  Udgivet: (2008)
• Binding and Inactivation Mechanism of a Humanized Fatty Acid Amide Hydrolase by α-Ketoheterocycle Inhibitors Revealed from Co-Crystal Structures
  af: Mileni, Mauro, et al.
  Udgivet: (2009)
• Exploration of a fundamental substituent effect of α-ketoheterocycle enzyme inhibitors: potent and selective inhibitors of fatty acid amide hydrolase
  af: DeMartino, Jessica K., et al.
  Udgivet: (2008)
• Optimization of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase
  af: Kimball, F. Scott, et al.
  Udgivet: (2008)