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Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages.

Several classes of oligonucleotide antisense compounds of sequence complementary to the start of the mRNA coding sequence for chloramphenicol acetyl transferase (CAT), including methylphosphonate, alkyltriester, and phosphorothioate analogues of DNA, have been compared to "normal" phosphod...

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Detalles Bibliográficos
Main Authors: Marcus-Sekura, C J, Woerner, A M, Shinozuka, K, Zon, G, Quinnan, G V
Formato: Artigo
Idioma:Inglês
Publicado: 1987
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC306020/
https://ncbi.nlm.nih.gov/pubmed/3475677
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