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Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages.

Several classes of oligonucleotide antisense compounds of sequence complementary to the start of the mRNA coding sequence for chloramphenicol acetyl transferase (CAT), including methylphosphonate, alkyltriester, and phosphorothioate analogues of DNA, have been compared to "normal" phosphodiester oli...

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Publicat a:Nucleic Acids Res
Autors principals: Marcus-Sekura, C J, Woerner, A M, Shinozuka, K, Zon, G, Quinnan, G V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1987
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3475677/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.14.5749
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