Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions

Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop stable EET analogs and test their in vivo blood pressure lowering effects in hypertensive rats. Using the pharmacophoric moiety of EETs, eth...

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Autors principals: Imig, John D., Elmarakby, Ahmed, Nithipatikom, Kasem, Wei, Shouzou, Capdevila, Jorge H., Tuniki, Venugopal Raju, Sangras, Bhavani, Anjaiah, Siddam, Manthati, Vijaya L., Sudarshan Reddy, D., Falck, John R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2010
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059925/
https://ncbi.nlm.nih.gov/pubmed/21423396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2010.00157
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