PHOSPHATIDYLSERINE REDUCES IMMUNE RESPONSE AGAINST HUMAN RECOMBINANT FVIII IN HEMOPHILIA A MICE BY REGULATION OF DENDRITIC CELL FUNCTION

A major clinical complication in the treatment of Hemophilia A using exogenously administered recombinant Factor VIII (FVIII) is the development of neutralizing antibodies. It has been shown previously that FVIII complexed with phosphatidylserine (PS) reduces the development of total and neutralizin...

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Hlavní autoři: Gaitonde, Puneet, Peng, Aaron, Straubinger, Robert M., Bankert, Richard B., Balu-Iyer, Sathy V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059555/
https://ncbi.nlm.nih.gov/pubmed/21094627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.10.006
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