PHOSPHATIDYLSERINE REDUCES IMMUNE RESPONSE AGAINST HUMAN RECOMBINANT FVIII IN HEMOPHILIA A MICE BY REGULATION OF DENDRITIC CELL FUNCTION

A major clinical complication in the treatment of Hemophilia A using exogenously administered recombinant Factor VIII (FVIII) is the development of neutralizing antibodies. It has been shown previously that FVIII complexed with phosphatidylserine (PS) reduces the development of total and neutralizin...

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Hauptverfasser: Gaitonde, Puneet, Peng, Aaron, Straubinger, Robert M., Bankert, Richard B., Balu-Iyer, Sathy V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059555/
https://ncbi.nlm.nih.gov/pubmed/21094627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.10.006
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