PHOSPHATIDYLSERINE REDUCES IMMUNE RESPONSE AGAINST HUMAN RECOMBINANT FVIII IN HEMOPHILIA A MICE BY REGULATION OF DENDRITIC CELL FUNCTION

A major clinical complication in the treatment of Hemophilia A using exogenously administered recombinant Factor VIII (FVIII) is the development of neutralizing antibodies. It has been shown previously that FVIII complexed with phosphatidylserine (PS) reduces the development of total and neutralizin...

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Detalhes bibliográficos
Main Authors: Gaitonde, Puneet, Peng, Aaron, Straubinger, Robert M., Bankert, Richard B., Balu-Iyer, Sathy V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059555/
https://ncbi.nlm.nih.gov/pubmed/21094627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.10.006
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