Differential regulation of BACE1 expression by oxidative and nitrosative signals

BACKGROUND: It is well established that both cerebral hypoperfusion/stroke and type 2 diabetes are risk factors for Alzheimer's disease (AD). Recently, the molecular link between ischemia/hypoxia and amyloid precursor protein (APP) processing has begun to be established. However, the role of th...

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Main Authors: Kwak, Young-Don, Wang, Ruishan, Li, Jing Jing, Zhang, Yun-Wu, Xu, Huaxi, Liao, Francesca-Fang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059281/
https://ncbi.nlm.nih.gov/pubmed/21371311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-17
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