APP Regulates NGF Receptor Trafficking and NGF-Mediated Neuronal Differentiation and Survival

β-amyloid precursor protein (APP) is a key factor in Alzheimer's disease (AD) but its physiological function is largely undetermined. APP has been found to regulate retrograde transport of nerve growth factor (NGF), which plays a crucial role in mediating neuronal survival and differentiation....

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Yun-wu, Chen, Yaomin, Liu, Yun, Zhao, Yingjun, Liao, Francesca-Fang, Xu, Huaxi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815101/
https://ncbi.nlm.nih.gov/pubmed/24224055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080571
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