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5-HT(2C)Rs Expressed by Pro-opiomelanocortin Neurons Regulate Insulin Sensitivity in Liver
Mice lacking 5-HT 2C receptors (5-HT(2C)Rs) displayed insulin resistance in the liver, a phenotype normalized by re-expression of 5-HT(2C)Rs only in pro-opiomelanocortin (POMC) neurons. 5-HT(2C)R deficiency also abolished anti-diabetic effects of mCPP (a 5-HT(2C)R agonist) while such effects were re...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059249/ https://ncbi.nlm.nih.gov/pubmed/21037584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2664 |
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