5-HT(2C)Rs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis

Drugs activating 5-hydroxytryptamine 2C receptors (5-HT(2C)Rs) potently suppress appetite, but the underlying mechanisms for these effects are not fully understood. To tackle this issue, we generated mice with global 5-HT(2C)R deficiency (2C null) and mice with 5-HT(2C)Rs re-expression only in pro-o...

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Detalhes bibliográficos
Main Authors: Xu, Yong, Jones, Juli E., Kohno, Daisuke, Williams, Kevin W., Lee, Charlotte E., Choi, Michelle J., Anderson, Jason G., Heisler, Lora K., Zigman, Jeffrey M., Lowell, Bradford B., Elmquist, Joel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2008
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631191/
https://ncbi.nlm.nih.gov/pubmed/19038216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.09.033
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