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‘Role reversal’ for the receptor PAR1 in sepsis-induced vascular damage

Sepsis is a deadly disease characterized by considerable derangement of the proinflammatory, anti-inflammatory and coagulation responses. Protease-activated receptor 1 (PAR1), an important regulator of endothelial barrier function and blood coagulation, has been proposed to be involved in the lethal...

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Detalles Bibliográficos
Main Authors: Kaneider, Nicole C, Leger, Andrew J, Agarwal, Anika, Nguyen, Nga, Perides, George, Derian, Claudia, Covic, Lidija, Kuliopulos, Athan
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059149/
https://ncbi.nlm.nih.gov/pubmed/17965715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1525
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