Amphipathic Tail-anchoring Peptide and Bcl-2 Homology Domain-3 (BH3) Peptides from Bcl-2 Family Proteins Induce Apoptosis through Different Mechanisms

Bcl-2 homology domain-3 (BH3) peptides are potent cancer therapeutic reagents that target regulators of apoptotic cell death in cancer cells. However, their cytotoxic effects are affected by different expression levels of Bcl-2 family proteins. We recently found that the amphipathic tail-anchoring p...

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Detalhes bibliográficos
Main Authors: Ko, Jae-Kyun, Choi, Kyoung-Han, Peng, Jun, He, Feng, Zhang, Zhi, Weisleder, Noah, Lin, Jialing, Ma, Jianjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059050/
https://ncbi.nlm.nih.gov/pubmed/21189256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198457
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