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Structure-Activity Analysis of Cathepsin K/Chondroitin 4-Sulfate Interactions
In the presence of oligomeric chondroitin 4-sulfate (C4-S), cathepsin K (catK) forms a specific complex that was shown to be the source of the major collagenolytic activity in bone osteoclasts. C4-S forms multiple contacts with amino acid residues on the backside of the catK molecule that help to fa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058997/ https://ncbi.nlm.nih.gov/pubmed/21193413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126706 |
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