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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
The role of autophagy, a lysosomal degradation pathway which prevents cellular damage, in the maintenance of adult mouse hematopoietic stem cells (HSCs) remains unknown. Although normal HSCs sustain life-long hematopoiesis, malignant transformation of HSCs leads to leukemia. Therefore, mechanisms pr...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058574/ https://ncbi.nlm.nih.gov/pubmed/21339326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101145 |
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