Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc mouse, a mouse model with impaired endochondral ossification caused by a loss of osteoclast (OCL) activi...

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Bibliographic Details
Main Authors: Mansour, Anna, Abou-Ezzi, Grazia, Sitnicka, Ewa, W. Jacobsen, Sten Eirik, Wakkach, Abdelilah, Blin-Wakkach, Claudine
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302238/
https://ncbi.nlm.nih.gov/pubmed/22351931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110994
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