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Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc mouse, a mouse model with impaired endochondral ossification caused by a loss of osteoclast (OCL) activi...

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Detalhes bibliográficos
Main Authors: Mansour, Anna, Abou-Ezzi, Grazia, Sitnicka, Ewa, W. Jacobsen, Sten Eirik, Wakkach, Abdelilah, Blin-Wakkach, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302238/
https://ncbi.nlm.nih.gov/pubmed/22351931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110994
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