Osteoclast activity modulates B-cell development in the bone marrow

B-cell development is dependent on the interactions between B-cell precursors and bone marrow stromal cells, but the role of osteoclasts (OCLs) in this process remains unknown. B lymphocytopenia is a characteristic of osteopetrosis, suggesting a modulation of B lymphopoiesis by OCL activity. To addr...

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Autori principali: Mansour, Anna, Anginot, Adrienne, Mancini, Stéphane J C, Schiff, Claudine, Carle, Georges F, Wakkach, Abdelilah, Blin-Wakkach, Claudine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193501/
https://ncbi.nlm.nih.gov/pubmed/21321604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.21
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