Mos activates MAP kinase in mouse oocytes through two opposite pathways
Activation of mitogen-activated protein kinase (MAPK) in maturing mouse oocytes occurs after synthesis of Mos, a MAPKKK. To investigate whether Mos acts only through MEK1, we microinjected constitutively active forms of MEK1 (MEK1S218D/S222D referred herein as MEK*) and Raf (ΔRaf) into mouse oocytes...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080153/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6065 |
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