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Importin α-regulated nucleation of microtubules by TPX2

The importin α-regulated microtubule-associated protein TPX2 is known to be critical for meiotic and mitotic spindle formation in vertebrates, but its detailed mechanism of action and regulation is not understood. Here, the site of interaction on TPX2 for importin α is mapped. A TPX2 mutant that can...

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Detalhes bibliográficos
Main Authors: Schatz, Christoph A., Santarella, Rachel, Hoenger, Andreas, Karsenti, Eric, Mattaj, Iain W., Gruss, Oliver J., Carazo-Salas, Rafael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156067/
https://ncbi.nlm.nih.gov/pubmed/12727873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg195
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