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Importin α-regulated nucleation of microtubules by TPX2

The importin α-regulated microtubule-associated protein TPX2 is known to be critical for meiotic and mitotic spindle formation in vertebrates, but its detailed mechanism of action and regulation is not understood. Here, the site of interaction on TPX2 for importin α is mapped. A TPX2 mutant that can...

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Bibliografiske detaljer
Main Authors: Schatz, Christoph A., Santarella, Rachel, Hoenger, Andreas, Karsenti, Eric, Mattaj, Iain W., Gruss, Oliver J., Carazo-Salas, Rafael E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156067/
https://ncbi.nlm.nih.gov/pubmed/12727873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg195
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