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Importin α-regulated nucleation of microtubules by TPX2

The importin α-regulated microtubule-associated protein TPX2 is known to be critical for meiotic and mitotic spindle formation in vertebrates, but its detailed mechanism of action and regulation is not understood. Here, the site of interaction on TPX2 for importin α is mapped. A TPX2 mutant that can...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Schatz, Christoph A., Santarella, Rachel, Hoenger, Andreas, Karsenti, Eric, Mattaj, Iain W., Gruss, Oliver J., Carazo-Salas, Rafael E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg195
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