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Importin α-regulated nucleation of microtubules by TPX2

The importin α-regulated microtubule-associated protein TPX2 is known to be critical for meiotic and mitotic spindle formation in vertebrates, but its detailed mechanism of action and regulation is not understood. Here, the site of interaction on TPX2 for importin α is mapped. A TPX2 mutant that can...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Schatz, Christoph A., Santarella, Rachel, Hoenger, Andreas, Karsenti, Eric, Mattaj, Iain W., Gruss, Oliver J., Carazo-Salas, Rafael E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg195
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