Mos activates MAP kinase in mouse oocytes through two opposite pathways

Activation of mitogen-activated protein kinase (MAPK) in maturing mouse oocytes occurs after synthesis of Mos, a MAPKKK. To investigate whether Mos acts only through MEK1, we microinjected constitutively active forms of MEK1 (MEK1S218D/S222D referred herein as MEK*) and Raf (ΔRaf) into mouse oocytes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Verlhac, Marie-Hélène, Lefebvre, Christophe, Kubiak, Jacek Z., Umbhauer, Muriel, Rassinier, Pascale, Colledge, William, Maro, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2000
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC305841/
https://ncbi.nlm.nih.gov/pubmed/11080153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6065
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