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Regulation of p53 activity in nuclear bodies by a specific PML isoform

Covalent modification of the promyelocytic leukaemia protein (PML) by SUMO-1 is a prerequisite for the assembly of nuclear bodies (NBs), subnuclear structures disrupted in various human diseases and linked to transcriptional and growth control. Here we demonstrate that p53 is recruited into NBs by a...

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שמור ב:
הוצא לאור ב:EMBO J
Principais autores: Fogal, Valentina, Gostissa, Monica, Sandy, Peter, Zacchi, Paola, Sternsdorf, Thomas, Jensen, Kirsten, Pandolfi, Pier Paolo, Will, Hans, Schneider, Claudio, Del Sal, Giannino
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2000
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6185
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