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Regulation of p53 activity in nuclear bodies by a specific PML isoform

Covalent modification of the promyelocytic leukaemia protein (PML) by SUMO-1 is a prerequisite for the assembly of nuclear bodies (NBs), subnuclear structures disrupted in various human diseases and linked to transcriptional and growth control. Here we demonstrate that p53 is recruited into NBs by a...

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Bibliografski detalji
Glavni autori: Fogal, Valentina, Gostissa, Monica, Sandy, Peter, Zacchi, Paola, Sternsdorf, Thomas, Jensen, Kirsten, Pandolfi, Pier Paolo, Will, Hans, Schneider, Claudio, Del Sal, Giannino
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305840/
https://ncbi.nlm.nih.gov/pubmed/11080164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6185
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