Regulation of p53 activity in nuclear bodies by a specific PML isoform

Covalent modification of the promyelocytic leukaemia protein (PML) by SUMO-1 is a prerequisite for the assembly of nuclear bodies (NBs), subnuclear structures disrupted in various human diseases and linked to transcriptional and growth control. Here we demonstrate that p53 is recruited into NBs by a...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Fogal, Valentina, Gostissa, Monica, Sandy, Peter, Zacchi, Paola, Sternsdorf, Thomas, Jensen, Kirsten, Pandolfi, Pier Paolo, Will, Hans, Schneider, Claudio, Del Sal, Giannino
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6185
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