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Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells

Abstract Background Promyelocytic leukemia protein (PML) is a primary component of PML nuclear bodies (PML-NBs). PML and PML-NBs play critical roles in processes like the cell cycle, DNA damage repair, apoptosis, and the antiviral immune response. Previously, we identified five porcine PML alternati...

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Principais autores: Zhenyu Chen, Huaijin Liu, Jingjing Zhu, Xing Duan, Han Wang, Xiangchen Li, Xiaolong Zhou, Ayong Zhao, Songbai Yang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:Virology Journal
Fag:
Porcine
PML isoforms
JEV
IFN-β
IRF3
Online adgang:https://doi.org/10.1186/s12985-023-02212-x
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