Regulation of p53 activity in nuclear bodies by a specific PML isoform
Covalent modification of the promyelocytic leukaemia protein (PML) by SUMO-1 is a prerequisite for the assembly of nuclear bodies (NBs), subnuclear structures disrupted in various human diseases and linked to transcriptional and growth control. Here we demonstrate that p53 is recruited into NBs by a...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6185 |
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