A non-redundant role for mouse Serpinb3a in the induction of mucus production in asthma

BACKGROUND: Asthma is a major public health burden worldwide. Studies from our group and others have demonstrated that SERPINB3 and B4 are induced in asthmatics; however their mechanistic role in asthma has yet to be determined. OBJECTIVE: To evaluate the role of Serpin3a, the murine homolog of huma...

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Hauptverfasser: Sivaprasad, Umasundari, Askew, David J., Ericksen, Mark B., Gibson, Aaron M., Stier, Matthew T., Brandt, Eric, Bass, Stacey A., Daines, Michael O., Chakir, Jamila, Stringer, Keith F., Wert, Susan E., Whitsett, Jeffrey A., Le Cras, Timothy D., Wills-Karp, Marsha, Silverman, Gary A., Khurana Hershey, Gurjit K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058372/
https://ncbi.nlm.nih.gov/pubmed/21126757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.10.009
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