Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor α2 in vivo

BACKGROUND: IL-13 receptor α2 (IL-13Rα2) is a high-affinity receptor for IL-13, a central mediator of allergic asthma. It acts predominantly as a decoy receptor but can also contribute to IL-13 responses under certain conditions. IL-13Rα2 exists in soluble and membrane forms, which can both bind IL-...

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Autori principali: Chen, Weiguo, Tabata, Yasuhiro, Gibson, Aaron M., Daines, Michael O., Warrier, Manoj R., Wills-Karp, Marsha, Khurana Hershey, Gurjit K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770158/
https://ncbi.nlm.nih.gov/pubmed/18694590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.06.022
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