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IL-13 Receptor Alpha 2 Membrane and Soluble Isoforms Differ in Human and Mouse
Although mice have ng/ml serum levels of soluble (s) IL-13Rα2, humans lack sIL-13Rα2 in serum. Our data provide a mechanism for this biologic divergence. In mice, discrete transcripts encoding s and membrane (mem) forms of IL-13Rα2 are generated by alternative splicing. We utilized siRNA to specific...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822278/ https://ncbi.nlm.nih.gov/pubmed/20007572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901028 |
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