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Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity
In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor (TCF) family, thereby stimulating the transcription of specific target genes. We recently identified Po...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6121 |
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