Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity

In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor (TCF) family, thereby stimulating the transcription of specific target genes. We recently identified Po...

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Main Authors: Bauer, Andreas, Chauvet, Sophie, Huber, Otmar, Usseglio, Fabrice, Rothbächer, Ute, Aragnol, Denise, Kemler, Rolf, Pradel, Jacques
格式: Artigo
語言:Inglês
出版: Oxford University Press 2000
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC305835/
https://ncbi.nlm.nih.gov/pubmed/11080158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6121
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