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Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity
In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor (TCF) family, thereby stimulating the transcription of specific target genes. We recently identified Po...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305835/ https://ncbi.nlm.nih.gov/pubmed/11080158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6121 |
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