Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity

In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor (TCF) family, thereby stimulating the transcription of specific target genes. We recently identified Po...

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Hlavní autoři: Bauer, Andreas, Chauvet, Sophie, Huber, Otmar, Usseglio, Fabrice, Rothbächer, Ute, Aragnol, Denise, Kemler, Rolf, Pradel, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305835/
https://ncbi.nlm.nih.gov/pubmed/11080158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6121
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