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Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4

Far1 is a bifunctional protein that is required to arrest the cell cycle and establish cell polarity during yeast mating. Here we show that SCF(Cdc4) ubiquitylates Far1 in the nucleus, which in turn targets the multi-ubiquitylated protein to 26S proteasomes most likely located at the nuclear envelop...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Blondel, Marc, Galan, Jean-Marc, Chi, Yong, Lafourcade, Céline, Longaretti, Céline, Deshaies, Raymond J., Peter, Matthias
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC305831/
https://ncbi.nlm.nih.gov/pubmed/11080155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6085
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