Vav-2 controls NFAT-dependent transcription inB- but not T-lymphocytes
We show here that Vav-2 is tyrosine phosphorylated following antigen receptor engagement in both B- and T-cells, but potentiates nuclear factor of activated T cells (NFAT)-dependent transcription only in B cells. Vav-2 function requires the N-terminus, as well as functional Dbl homology and SH2 doma...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6173 |
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