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Vav-2 controls NFAT-dependent transcription inB- but not T-lymphocytes
We show here that Vav-2 is tyrosine phosphorylated following antigen receptor engagement in both B- and T-cells, but potentiates nuclear factor of activated T cells (NFAT)-dependent transcription only in B cells. Vav-2 function requires the N-terminus, as well as functional Dbl homology and SH2 doma...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305817/ https://ncbi.nlm.nih.gov/pubmed/11080163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6173 |
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