Vav-2 controls NFAT-dependent transcription inB- but not T-lymphocytes

We show here that Vav-2 is tyrosine phosphorylated following antigen receptor engagement in both B- and T-cells, but potentiates nuclear factor of activated T cells (NFAT)-dependent transcription only in B cells. Vav-2 function requires the N-terminus, as well as functional Dbl homology and SH2 doma...

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書目詳細資料

發表在:	EMBO J
Principais autores:	Doody, Gina M., Billadeau, Daniel D., Clayton, Elizabeth, Hutchings, Amanda, Berland, Robert, McAdam, Simon, Leibson, Paul J., Turner, Martin
格式:	Artigo
語言:	Inglês
出版:	Nature Publishing Group 2000
主題:	Articles
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11080163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.22.6173
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