Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common abnormalities in human cancer. Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer. METHODS:...

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Dades bibliogràfiques
Autors principals: Bièche, Ivan, Vacher, Sophie, Lallemand, François, Tozlu-Kara, Sengül, Bennani, Hind, Beuzelin, Michèle, Driouch, Keltouma, Rouleau, Etienne, Lerebours, Florence, Ripoche, Hugues, Cizeron-Clairac, Géraldine, Spyratos, Frédérique, Lidereau, Rosette
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058099/
https://ncbi.nlm.nih.gov/pubmed/21352579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-23
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