Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common abnormalities in human cancer. Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer. METHODS:...

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主要な著者: Bièche, Ivan, Vacher, Sophie, Lallemand, François, Tozlu-Kara, Sengül, Bennani, Hind, Beuzelin, Michèle, Driouch, Keltouma, Rouleau, Etienne, Lerebours, Florence, Ripoche, Hugues, Cizeron-Clairac, Géraldine, Spyratos, Frédérique, Lidereau, Rosette
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058099/
https://ncbi.nlm.nih.gov/pubmed/21352579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-23
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