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Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common abnormalities in human cancer. Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer. METHODS:...

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Detaylı Bibliyografya
Asıl Yazarlar: Bièche, Ivan, Vacher, Sophie, Lallemand, François, Tozlu-Kara, Sengül, Bennani, Hind, Beuzelin, Michèle, Driouch, Keltouma, Rouleau, Etienne, Lerebours, Florence, Ripoche, Hugues, Cizeron-Clairac, Géraldine, Spyratos, Frédérique, Lidereau, Rosette
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058099/
https://ncbi.nlm.nih.gov/pubmed/21352579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-23
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