PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

INTRODUCTION: PIK3CA is the oncogene showing the highest frequency of gain-of-function mutations in breast cancer, but the prognostic value of PIK3CA mutation status is controversial. METHODS: We investigated the prognostic significance of PIK3CA mutation status in a series of 452 patients with unil...

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Autori principali: Cizkova, Magdalena, Susini, Aurélie, Vacher, Sophie, Cizeron-Clairac, Géraldine, Andrieu, Catherine, Driouch, Keltouma, Fourme, Emmanuelle, Lidereau, Rosette, Bièche, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496146/
https://ncbi.nlm.nih.gov/pubmed/22330809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3113
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